このアイテムのアクセス数: 82
このアイテムのファイル:
| ファイル | 記述 | サイズ | フォーマット | |
|---|---|---|---|---|
| j.gore.2022.101115.pdf | 3.87 MB | Adobe PDF | 見る/開く |
完全メタデータレコード
| DCフィールド | 値 | 言語 |
|---|---|---|
| dc.contributor.author | Yoshimura, Kayoko | en |
| dc.contributor.author | Yamanoi, Koji | en |
| dc.contributor.author | Kanai, Masashi | en |
| dc.contributor.author | Okunomiya, Asuka | en |
| dc.contributor.author | Sagae, Yusuke | en |
| dc.contributor.author | Sunada, Masumi | en |
| dc.contributor.author | Taki, Mana | en |
| dc.contributor.author | Ukita, Masayo | en |
| dc.contributor.author | Chigusa, Yoshitsugu | en |
| dc.contributor.author | Horie, Akihito | en |
| dc.contributor.author | Yamaguchi, Ken | en |
| dc.contributor.author | Hamanishi, Junzo | en |
| dc.contributor.author | Minamiguchi, Sachiko | en |
| dc.contributor.author | Yamamoto, Noboru | en |
| dc.contributor.author | Muto, Manabu | en |
| dc.contributor.author | Mandai, Masaki | en |
| dc.contributor.alternative | 吉村, 佳与子 | ja |
| dc.contributor.alternative | 山ノ井, 康二 | ja |
| dc.contributor.alternative | 金井, 雅史 | ja |
| dc.contributor.alternative | 奥宮, 明日香 | ja |
| dc.contributor.alternative | 寒河江, 悠介 | ja |
| dc.contributor.alternative | 砂田, 真澄 | ja |
| dc.contributor.alternative | 滝, 真奈 | ja |
| dc.contributor.alternative | 浮田, 真沙世 | ja |
| dc.contributor.alternative | 千草, 義継 | ja |
| dc.contributor.alternative | 堀江, 昭史 | ja |
| dc.contributor.alternative | 山口, 建 | ja |
| dc.contributor.alternative | 濵西, 潤三 | ja |
| dc.contributor.alternative | 南口, 早智子 | ja |
| dc.contributor.alternative | 武藤, 学 | ja |
| dc.contributor.alternative | 万代, 昌紀 | ja |
| dc.date.accessioned | 2023-08-18T00:20:50Z | - |
| dc.date.available | 2023-08-18T00:20:50Z | - |
| dc.date.issued | 2022-12 | - |
| dc.identifier.uri | http://hdl.handle.net/2433/284687 | - |
| dc.description.abstract | Mature cystic teratoma of the ovary (MCT) occasionally undergoes malignant transformation (MT) that is resistant to chemotherapy and has a poor prognosis. We experienced a case of clinically aggressive MCT-MT that invades surrounding organs and tissues. Although tumor was resected entirely, a rapid tumor recurrence occurred during postoperative chemotherapy (paclitaxel + ifosfamide + cisplatin). The results of comprehensive genomic profiling test performed early in the postoperative period showed a high tumor mutational burden of 23 mutations/Mb. Treatment with nivolumab monotherapy has promptly been initiated and has been very successful for more than one year. | en |
| dc.language.iso | eng | - |
| dc.publisher | Elsevier BV | en |
| dc.rights | © 2022 The Author(s). Published by Elsevier Inc. | en |
| dc.rights | This is an open access article under the CC BY-NC-ND license. | en |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | - |
| dc.subject | Malignant transformation of mature cystic teratoma | en |
| dc.subject | Immune checkpoint inhibitor | en |
| dc.subject | Comprehensive genomic profiling test | en |
| dc.subject | PD-L1 | en |
| dc.subject | Tumor mutation burden | en |
| dc.title | Nivolumab for malignant transformation of ovarian mature cystic teratoma | en |
| dc.type | journal article | - |
| dc.type.niitype | Journal Article | - |
| dc.identifier.jtitle | Gynecologic Oncology Reports | en |
| dc.identifier.volume | 44 | - |
| dc.relation.doi | 10.1016/j.gore.2022.101115 | - |
| dc.textversion | publisher | - |
| dc.identifier.artnum | 101115 | - |
| dc.identifier.pmid | 36560959 | - |
| dcterms.accessRights | open access | - |
| dc.identifier.eissn | 2352-5789 | - |
| 出現コレクション: | 学術雑誌掲載論文等 | |
このアイテムは次のライセンスが設定されています: クリエイティブ・コモンズ・ライセンス
