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dc.contributor.authorSasaki-Honda, Mitsuruen
dc.contributor.authorAkatsuka, Kyokoen
dc.contributor.authorSawai, Tsutomuen
dc.contributor.alternative本田, 充ja
dc.contributor.alternative赤塚, 京子ja
dc.contributor.alternative澤井, 努ja
dc.date.accessioned2023-11-15T02:38:21Z-
dc.date.available2023-11-15T02:38:21Z-
dc.date.issued2023-11-14-
dc.identifier.urihttp://hdl.handle.net/2433/286050-
dc.description科学の最新動向を基に、エピゲノム編集の倫理・規制を議論. 京都大学プレスリリース. 2023-11-03.ja
dc.descriptionPotential inheritable effects and ethical considerations of epigenome editing. 京都大学プレスリリース. 2023-11-03.en
dc.description.abstractEpigenome editing offers ethical advantages with non-inheritable gene expression control. However, concerns arise regarding potential transgenerational effects in humans. Ethical and regulatory evaluation is crucial, considering recent advancements and enhanced understanding of transgenerational epigenetics in both mammals and humans.en
dc.language.isoeng-
dc.publisherElsevier BVen
dc.rights© 2023 The Author(s).en
dc.rightsThis is an open access article under the CC BY-NC-ND license.en
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/-
dc.titleIs epigenome editing non-inheritable? Implications for ethics and the regulation of human applicationsen
dc.typejournal article-
dc.type.niitypeJournal Article-
dc.identifier.jtitleStem Cell Reportsen
dc.identifier.volume18-
dc.identifier.issue11-
dc.identifier.spage2005-
dc.identifier.epage2009-
dc.relation.doi10.1016/j.stemcr.2023.10.003-
dc.textversionpublisher-
dc.addressDepartment of Clinical Application, Center for iPS Cell Research and Application, Kyoto University; Institute of Biomedicine and Biotechnology of Cantabria, CSIC/Universidad de Cantabriaen
dc.addressUehiro Research Division for iPS Cell Ethics, Center for iPS Cell Research and Application, Kyoto Universityen
dc.addressGraduate School of Humanities and Social Sciences, Hiroshima University; Institute for the Advanced Study of Human Biology, Kyoto University; Centre for Biomedical Ethics, Yong Loo Lin School of Medicine, National University of Singaporeen
dc.identifier.pmid37922912-
dc.relation.urlhttps://ashbi.kyoto-u.ac.jp/ja/news/20231102_research-result_tsutomu-sawai/-
dc.relation.urlhttps://ashbi.kyoto-u.ac.jp/news/20231102_research-result_tsutomu-sawai/-
dcterms.accessRightsopen access-
datacite.awardNumber21K12908-
datacite.awardNumber.urihttps://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21K12908/-
dc.identifier.eissn2213-6711-
jpcoar.funderName日本学術振興会ja
jpcoar.awardTitle経験的生命倫理学における方法論の構築とその応用ja
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