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dc.contributor.author | Shinohara, Koh | en |
dc.contributor.author | Murase, Kazunori | en |
dc.contributor.author | Tsuchido, Yasuhiro | en |
dc.contributor.author | Noguchi, Taro | en |
dc.contributor.author | Yukawa, Satomi | en |
dc.contributor.author | Yamamoto, Masaki | en |
dc.contributor.author | Matsumura, Yasufumi | en |
dc.contributor.author | Nakagawa, Ichiro | en |
dc.contributor.author | Nagao, Miki | en |
dc.contributor.alternative | 篠原, 浩 | ja |
dc.contributor.alternative | 村瀬, 一典 | ja |
dc.contributor.alternative | 土戸, 康弘 | ja |
dc.contributor.alternative | 野口, 太郎 | ja |
dc.contributor.alternative | 湯川, 理己 | ja |
dc.contributor.alternative | 山本, 正樹 | ja |
dc.contributor.alternative | 松村, 康史 | ja |
dc.contributor.alternative | 中川, 一路 | ja |
dc.contributor.alternative | 長尾, 美紀 | ja |
dc.date.accessioned | 2024-03-01T01:26:42Z | - |
dc.date.available | 2024-03-01T01:26:42Z | - |
dc.date.issued | 2023-03 | - |
dc.identifier.uri | http://hdl.handle.net/2433/287144 | - |
dc.description.abstract | Incidence of Streptococcus dysgalactiae subspecies equisimilis (SDSE) bacteremia is increasing in the Kyoto-Shiga region of Japan. We retrospectively analyzed clinical features of SDSE bacteremia and conducted comparative genomic analyses of isolates collected from 146 bacteremia episodes among 133 patients during 2005-2021. Of those patients, 7.7% required vasopressor support, and 7.0% died while in the hospital. The prevalence of isolates resistant to erythromycin, minocycline, and clindamycin increased from 8.6% during 2005-2017 to 21.6% during 2018-2021. Our genomic analysis demonstrated that sequence type 525 and clonal complex 25 were predominant in SDSE isolates collected during 2018-2021. In addition, those isolates had acquired 2 antimicrobial-resistance genes, ermB and tetM, via Tn916-like integrative and conjugative elements (ICEs). Phylogenetic analysis revealed clonal distribution of Tn916-like ICEs in SDSE isolates. Our findings suggest that Tn916-like ICEs contributed to the emergence and recent increase of multidrug-resistant SDSE bacteremia in this region of Japan. | en |
dc.language.iso | eng | - |
dc.publisher | Centers for Disease Control and Prevention (CDC) | en |
dc.rights | Public Domain | en |
dc.title | Clonal Expansion of Multidrug-Resistant <i>Streptococcus dysgalactiae</i> Subspecies <i>equisimilis</i> Causing Bacteremia, Japan, 2005–2021 | en |
dc.type | journal article | - |
dc.type.niitype | Journal Article | - |
dc.identifier.jtitle | Emerging Infectious Diseases | en |
dc.identifier.volume | 29 | - |
dc.identifier.issue | 3 | - |
dc.identifier.spage | 528 | - |
dc.identifier.epage | 539 | - |
dc.relation.doi | 10.3201/eid2903.221060 | - |
dc.textversion | publisher | - |
dc.identifier.pmid | 36823027 | - |
dcterms.accessRights | open access | - |
dc.identifier.pissn | 1080-6040 | - |
dc.identifier.eissn | 1080-6059 | - |
出現コレクション: | 学術雑誌掲載論文等 |
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