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j.ajic.2022.09.007.pdf | 1.07 MB | Adobe PDF | 見る/開く |
タイトル: | High mortality and morbidity among vaccinated residents infected with the SARS-CoV-2 Omicron variant during an outbreak in a nursing home in Kyoto City, Japan |
著者: | Matsumura, Yasufumi Yamamoto, Masaki Shinohara, Koh Tsuchido, Yasuhiro Yukawa, Satomi Noguchi, Taro Ikeda, Takeshi Nagao, Miki |
著者名の別形: | 松村, 康史 山本, 正樹 篠原, 浩 土戸, 康弘 湯川, 理己 野口, 太郎 長尾, 美紀 |
キーワード: | COVID-19 Viral genome Variant of concern Long-term care facility |
発行日: | Jul-2023 |
出版者: | Elsevier BV Association for Professionals in Infection Control and Epidemiology, Inc. |
誌名: | American Journal of Infection Control |
巻: | 51 |
号: | 7 |
開始ページ: | 800 |
終了ページ: | 806 |
抄録: | BACKGROUND: Outbreaks of coronavirus disease 2019 (COVID-19) in long-term care facilities are associated with mortality, although vaccination have contributed to improvements. This study reports clinical impacts of a COVID-19 outbreak in a nursing home for elderly individuals in Kyoto City, Japan. METHODS: We performed epidemiologic and molecular investigations of the outbreak and characterized outcomes of the nursing home residents. RESULTS: During the outbreak period, a total of 31 residents (39.2%) and 26 staff members (49.1%) were infected with COVID-19. All residents and staff received two doses of a vaccine approximately 7 months prior. Ten residents with severe hypoxemia could not be transferred to a hospital due to a shortage of beds for COVID-19 patients. Within 90 days of the onset of the outbreak, 8 residents with COVID-19 (25.8%) died. A total of 48.4% of residents with COVID-19 developed 1 or more comorbidities. Viral genome analysis showed that the outbreak was caused by the Omicron BA.1.1.2 variant. CONCLUSIONS: Despite vaccination, high mortality and morbidity were observed in the COVID-19 outbreak due to the Omicron variant. Limiting medical care for residents with COVID-19 in facilities that experience ongoing outbreaks may be needed to reduce the risk of mortality among nursing home residents. |
著作権等: | © 2022 The Author(s). Published by Elsevier Inc. on behalf of Association for Professionals in Infection Control and Epidemiology, Inc. This is an open access article under the CC BY license. |
URI: | http://hdl.handle.net/2433/287145 |
DOI(出版社版): | 10.1016/j.ajic.2022.09.007 |
PubMed ID: | 36116676 |
出現コレクション: | 学術雑誌掲載論文等 |
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