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Title: Extension of a DNA Molecule by Local Heating with a Laser
Authors: Ichikawa, Masatoshi  kyouindb  KAKEN_id  orcid (unconfirmed)
Ichikawa, Hiroki
Yoshikawa, Kenichi
Kimura, Yasuyuki
Author's alias: 吉川, 研一
Issue Date: Oct-2007
Publisher: American Physical Society
Citation: Masatoshi Ichikawa, Hiroki Ichikawa, Kenichi Yoshikawa, and Yasuyuki Kimura, “Extension of a DNA Molecule by Local Heating with a Laser”, PRL, 99 148104 (2007)
Journal title: Physical Review Letters
Volume: 99
Start page: 148104
Abstract: Thermal convection and thermophoresis induced by µm-scale local heating are shown to elongate a single DNA molecule. An infrared laser used as a point heat source is converged into a dispersion solution of DNA molecules, which is observed under a fluorescent microscope. The thermal convection around the laser focus manifests as extensional flow for the long DNA chain. A simulation of thermal convection that reproduces the experimental condition provides numerical support for the stretching caused by thermal convection. This DNA elongation technique is a novel method for manipulating the intact single DNA molecules, and it can be applied to a “lab on a chip”.
Rights: Copyright © 2007 American Physical Society
DOI(Published Version): 10.1103/PhysRevLett.99.148104
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