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タイトル: | Extension of a DNA Molecule by Local Heating with a Laser |
著者: | Ichikawa, Masatoshi https://orcid.org/0000-0002-6345-2106 (unconfirmed) Ichikawa, Hiroki Yoshikawa, Kenichi Kimura, Yasuyuki |
著者名の別形: | 吉川, 研一 |
発行日: | Oct-2007 |
出版者: | American Physical Society (APS) |
引用: | Masatoshi Ichikawa, Hiroki Ichikawa, Kenichi Yoshikawa, and Yasuyuki Kimura, “Extension of a DNA Molecule by Local Heating with a Laser”, PRL, 99 148104 (2007) |
誌名: | Physical Review Letters |
巻: | 99 |
開始ページ: | 148104 |
抄録: | Thermal convection and thermophoresis induced by µm-scale local heating are shown to elongate a single DNA molecule. An infrared laser used as a point heat source is converged into a dispersion solution of DNA molecules, which is observed under a fluorescent microscope. The thermal convection around the laser focus manifests as extensional flow for the long DNA chain. A simulation of thermal convection that reproduces the experimental condition provides numerical support for the stretching caused by thermal convection. This DNA elongation technique is a novel method for manipulating the intact single DNA molecules, and it can be applied to a “lab on a chip”. |
著作権等: | Copyright © 2007 American Physical Society |
URI: | http://hdl.handle.net/2433/49185 |
DOI(出版社版): | 10.1103/PhysRevLett.99.148104 |
PubMed ID: | 17930727 |
出現コレクション: | 学術雑誌掲載論文等 |
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