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タイトル: Studies on the Development of Inflammatory Lesions : I. Influences of Cortisone and Methylandrostendiol on Experimental Tuberculosis
著者: AMATSU, Masashi
著者名の別形: 天津, 正
発行日: 25-Jun-1956
出版者: Tuberculosis Research Institute, Kyoto University
誌名: Acta tuberculosea Japonica
巻: 6
号: 1
開始ページ: 49
終了ページ: 62
抄録: In this paper, the author observed the influences of various steroid hormones on tuberculous lesions as a part of the study in the general tissue reaction. Thirty guinea pigs were infected and then administered with several hormones at the 3rd week after the inoculation. At the various periods (the 5th, the 7th, the 10th and 20th week after the infection), the macroscopic and histological findings of the lesions were investigated. The following results were obtained; by the administration of cortisone or MAD (Methylandrostendiol), the patterns of the tuberculous lesions were greatly modified. Multiplication of fibroblasts and infiltration of lymphocytes were inhibited by the administration of cortisone in this experiment. On the other hand, fibroblastic response and proliferation of epithelioid cells were promoted by the administration of MAD according to its periods. Therfore MAD seems to hasten inflammatory process to the productive type. Due to the administration of MAD, a proliferation of small bile ducts of the tuberculous animals was also observed.
記述: この論文は国立情報学研究所の学術雑誌公開支援事業により電子化されました。
URI: http://hdl.handle.net/2433/51751
出現コレクション:Vol.6 No.1

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