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Title: 前立腺におけるエラスチンの分布
Other Titles: Distribution of elastic fiber on prostate
Authors: 杉本, 公一  KAKEN_name
松本, 成史  KAKEN_name
植村, 天受  KAKEN_name
伊藤, 浩行  KAKEN_name
Author's alias: Sugimoto, Koichi
Matsumoto, Seiji
Uemura, Hirotsugu
Ito, Hiroyuki
Keywords: Elastin
Issue Date: May-2008
Publisher: 泌尿器科紀要刊行会
Journal title: 泌尿器科紀要
Volume: 54
Issue: 5
Start page: 321
End page: 324
Abstract: 前立腺肥大症に対し前立腺被膜下切除術を施行された5例の前立腺標本と正常前立腺標本4例の合計9例を対象に, エラスチンの分布について検討した。その結果, 今回の前立腺における検討では定性分析(半定量分析)であったが, 前立腺肥大症症例の基部, 尖部においてエラスチンが豊富に存在することが判明した。また, 弾性線維の分布は, 前立腺部尿道付近, 前立腺被膜周囲に多く存在することが確認された。
We examined prostate specimens from 5 patients (median age; 71.8 years, range 57-83), with benign prostatic hyperplasia (BPH) removed during surgery, and 4 autopsied cadavers (median age at death; 68.8 years, range 46-92) who had either obstructive or neurogenic voiding dysfunction. The prostate specimens were severed anatomically into samples of the base, middle, and apex of the prostate. They served as samples for a comparative study of the distribution of elastin fibers by means of a pathology study, using the Elastica Van Gieson (EV) staining method. The number of pixels representing elastin fibers in computerized images was analyzed using Adobe Photoshop Ver. 2.0. There was a larger proportion of elastin in the area of the urethra and at the base of prostate than in the remainder of the organ. The percentage of elastin at the base of the prostate was significantly greater among BPH patients than cadavers. Thus, it was demonstrated that elastin a stromal component was increased in BPH patients.
Rights: 許諾条件により本文は2009-06-01に公開
PubMed ID: 18546854
Appears in Collections:Vol.54 No.5

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