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タイトル: | 後天性特発性低ゴナドトロピン性男子性腺機能低下症の1例 |
その他のタイトル: | A Case of Adult-Onset Idiopathic Hypogonadotropic Hypogonadism Presenting with Infertility |
著者: | 寺尾, 秀行 小川, 毅彦 柳澤, 昌宏 三宅, 見季 佐野, 太 喜多, かおる 村上, 貴之 槙山, 和秀 中井川, 昇 上村, 博司 矢尾, 正祐 窪田, 吉信 |
著者名の別形: | Terao, Hideyuki Ogawa, Takehiko Yanagisawa, Masahiro Miyake, Miki Sano, Futoshi Kita, Kaoru Murakami, Takayuki Makiyama, Kazuhide Nakaigawa, Noboru Uemura, Hiroji Yao, Masahiro Kubota, Yoshinobu |
キーワード: | Adult-onset Infertility Hypogonadotropic hypogonadism |
発行日: | Jul-2009 |
出版者: | 泌尿器科紀要刊行会 |
誌名: | 泌尿器科紀要 |
巻: | 55 |
号: | 7 |
開始ページ: | 437 |
終了ページ: | 439 |
抄録: | A 28-year-old man with adult-onset idiopathic male hypogonadotropic hypogonadism (MHH) is reported. He had been delivered normally and had normal puberty. He was referred to our hospital with a chief complaint of infertility. Serum levels of testosterone, luteinizing hormone, and follicle stimulating hormone (FSH) were low. Semen analysis demonstrated azoospermia. Pituitary hypofunction was suggested by gonadotropin releasing hormone (GnRH) loading test. Magnetic resonance images did not detect any abnormalities in the hypothalamic-pituitary region. After a diagnosis of adult-onset hypogonadotropic hypogonadism was established, the patient received human chorionic gonadotropin (hCG) and recombinant FSH treatment. After 5 months, his sperm count reached 6.9×106 per ml and his wife became pregnant. Adult-onset HH in most cases is caused by tumors and trauma. To our knowledge 17 cases of adult-onset idiopathic HH have been reported, and there were only 3 cases that were caused by pituitary dysfunction. This report showed that r-FSH and hCG therapy was effective in promoting fertility in a patient with adult-onset idiopathic MHH. |
著作権等: | 許諾条件により本文は2010-08-01に公開 |
URI: | http://hdl.handle.net/2433/84736 |
PubMed ID: | 19673435 |
出現コレクション: | Vol.55 No.7 |
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