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タイトル: | CA19-9 が高値を呈し膣壁浸潤を伴った女性尿道腺癌の1例 |
その他のタイトル: | A Case of Primary Urethral Adenocarcinoma Accompanied by Vaginal Wall Infiltration in which the CA19-9 Level was Very High |
著者: | 前川, 滋克 比島, 恒和 山田, 幸央 市川, 寛樹 夏井, 信輔 篠原, 充 |
著者名の別形: | Maekawa, Shigekatsu Hishima, Tsunekazu Yamada, Yukio Ichikawa, Hiroki Natsui, Shinsuke Shinohara, Mitsuru |
キーワード: | Urethral adenocarcinoma Vaginal wall invasion CA19-9 Female urethra |
発行日: | Aug-2009 |
出版者: | 泌尿器科紀要刊行会 |
誌名: | 泌尿器科紀要 |
巻: | 55 |
号: | 8 |
開始ページ: | 513 |
終了ページ: | 516 |
抄録: | A 55-year-old woman had urinary frequency and a constant urge to urinate. Computed tomography confirmed a urethral tumor, and transurethral biopsy confirmed adenocarcinoma. She visited our hospital to undergo treatment, and we performed an anterior pelvic excenteration. On histology, the tumor had spread to the bladder, urethra, and vagina. However, the majority of the tumor was located in the bladder and urethra, a duct with intestinal metaplasia was present around the urethra, and carcinoma in situ was seen in the urethral mucosa. Based on the above findings, the patient was diagnosed as having primary urethral adenocarcinoma. No tumor cells were seen in the resection stump. Six months after surgery, the patient developed bone metastasis, followed by peritoneal and pleural dissemination, as well as multiple lung metastases. The patient died nine months after surgery. In the present patient, the carbohydrate antigen (CA) 19-9 level changed with the clinical course, and it was a useful marker. Urethral tumor is relatively rare. A urethral tumor accompanied by vaginal wall infiltration is likely to be mistaken for a primary vaginal tumor. It was very difficult to identify the primary organ in our case. To the best of our knowledge, the present patient is the sixth reported case of primary urethral carcinoma accompanied by vaginal wall infiltration in Japan. The six reported cases are compared and analyzed. |
著作権等: | 許諾条件により本文は2010-09-01に公開 |
URI: | http://hdl.handle.net/2433/85237 |
PubMed ID: | 19764540 |
出現コレクション: | Vol.55 No.8 |
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