このアイテムのアクセス数: 345
このアイテムのファイル:
| ファイル | 記述 | サイズ | フォーマット | |
|---|---|---|---|---|
| j.bmcl.2008.10.018.pdf | 155.93 kB | Adobe PDF | 見る/開く |
完全メタデータレコード
| DCフィールド | 値 | 言語 |
|---|---|---|
| dc.contributor.author | Tanabe, Kazuhito | en |
| dc.contributor.author | Ebihara, Masahiko | en |
| dc.contributor.author | Hirata, Nao | en |
| dc.contributor.author | Nishimoto, Sei-ichi | en |
| dc.date.accessioned | 2009-10-06T05:37:39Z | - |
| dc.date.available | 2009-10-06T05:37:39Z | - |
| dc.date.issued | 2008-12-01 | - |
| dc.identifier.citation | Kazuhito Tanabe, Masahiko Ebihara, Nao Hirata and Sei-ichi Nishimoto. "Radiolytic one-electron reduction characteristics of tyrosine derivative caged by 2-oxopropyl group". Bioorganic & Medicinal Chemistry Letters. Vol.18, No.23, p.6126-6129, (2008). | - |
| dc.identifier.issn | 0960-894X | - |
| dc.identifier.uri | http://hdl.handle.net/2433/85295 | - |
| dc.description.abstract | We employed X-irradiation to activate a caged amino acid with a 2-oxoalkyl group. We designed and synthesized tyrosine derivative caged by a 2-oxoalkyl group (Tyr(Oxo)) to evaluate its radiolytic one-electron reduction characteristics in aqueous solution. Upon hypoxic X-irradiation, Tyr(Oxo) released a 2-oxopropyl group to form the corresponding uncaged tyrosine. In addition, radiolysis of dipeptides containing Tyr(Oxo) revealed that the efficiency of radiolytic removal of 2-oxopropyl group increased significantly by the presence of neighboring aromatic amino acids. | en |
| dc.language.iso | eng | - |
| dc.publisher | Elsevier Ltd | en |
| dc.rights | Copyright © 2008 Elsevier Ltd | en |
| dc.rights | This is not the published version. Please cite only the published version. | en |
| dc.rights | この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。 | ja |
| dc.subject | Caged tyrosine | en |
| dc.subject | 2-oxopropyl group | en |
| dc.subject | X-irradiation | en |
| dc.subject | Hypoxic conditions | en |
| dc.title | Radiolytic one-electron reduction characteristics of tyrosine derivative caged by 2-oxopropyl group | en |
| dc.type | journal article | - |
| dc.type.niitype | Journal Article | - |
| dc.identifier.ncid | AA1079577X | - |
| dc.identifier.jtitle | Bioorganic & Medicinal Chemistry Letters | en |
| dc.identifier.volume | 18 | - |
| dc.identifier.issue | 23 | - |
| dc.identifier.spage | 6126 | - |
| dc.identifier.epage | 6129 | - |
| dc.relation.doi | 10.1016/j.bmcl.2008.10.018 | - |
| dc.textversion | author | - |
| dc.identifier.pmid | 18930655 | - |
| dcterms.accessRights | open access | - |
| 出現コレクション: | 学術雑誌掲載論文等 | |
このリポジトリに保管されているアイテムはすべて著作権により保護されています。