ダウンロード数: 568
このアイテムのファイル:
| ファイル | 記述 | サイズ | フォーマット | |
|---|---|---|---|---|
| j.tet.2010.01.073.pdf | 834.41 kB | Adobe PDF | 見る/開く |
| タイトル: | Synthesis of 3,3-disubstituted oxindoles through Pd-catalyzed intramolecular cyanoamidation |
| 著者: | Yasui, Yoshizumi Kamisaki, Haruhi Ishida, Takayuki Takemoto, Yoshiji    https://orcid.org/0000-0003-1375-3821 (unconfirmed) |
| 著者名の別形: | 竹本, 佳司 |
| 発行日: | 13-Mar-2010 |
| 出版者: | Elsevier |
| 誌名: | Tetrahedron |
| 巻: | 66 |
| 号: | 11 |
| 開始ページ: | 1980 |
| 終了ページ: | 1989 |
| 抄録: | The cyanoamidation of olefins was achieved. When N-(2-vinylphenyl)cyanoformamides were treated with palladium catalyst, intramolecular cyanoamidation took place to give corresponding 3, 3-disubstituted oxindoles. P(t-Bu)3 showed a remarkable effect on this reaction. When it was used with Pd(dba)2, the reaction was completed in 15 min at 100 oC for many substrates. Furthermore, the enantioselective cyanoamidation was accomplished with Pd(dba)2 and an optically active phosphoramidite to provide optically active 3, 3-disubstituted oxindoles. Manipulation of the resulting oxindoles has been studied. |
| 著作権等: | c 2010 Elsevier Ltd. All rights reserved. この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。 This is not the published version. Please cite only the published version. |
| URI: | http://hdl.handle.net/2433/101563 |
| DOI(出版社版): | 10.1016/j.tet.2010.01.073 |
| 出現コレクション: | 学術雑誌掲載論文等 |
このリポジトリに保管されているアイテムはすべて著作権により保護されています。