精嚢の吸収生理に関する研究 第2編:精嚢の吸収作用にあける去勢の影響

Abstract

The author has already described in part I, the fact that various drugs were absorbed actively through the mucous membrane of the lumen of the seminal vesicles. As the testicular function has the most intimate relation to the absorption ability of the seminal vesicles, the investigation in this series was pointed to the influence of the testicular function upon the absorption ability of the seminal vesicles. The experimence was performed by injecting penicillin, streptomycin, tetracycline and chloramphenicol into the seminal vesicles through vas deferens of a full grown male rabbit which was castrated in advance, and examining the absorption ability of the seminal vesicles by the time elapsed. The results were as follows : 1) The absorption of penicillin began to decrease in five days after the castration and gradually dropped by the time elapsed. 2) Decrease of absorption ability to streptomycin appeared in three days after castration and continued dropping according to the t ime elapsed. 3 ) Absorption of tetracycline started decreasing from one week after castration. 4) Concerning the absorption of chloramphenicol, a sign of decrease appeared in two weeks after castration, but did not drop so rema rkably as the three other antibiotics even in three weeks. 5) In the histo-pathological examinations, th e tissues of the seminal vesicles showed degeneration in three weeks after castration, an d this change was in a accord with the decrease of absorption ability. 6) The decrease of the absorption ability after castration was caused chiefly by the disappearance of the testicular hormone and hyaluronid ase.