淋菌性及び非淋菌性尿道炎に関する研究 第V篇:非淋菌性尿道炎の細菌学的研究

Abstract

During 5 years from 1952 to 1956, 319 organism had been cultured from the male urethra of 412 cases with N.G.U., who visited the urological clinic of Kyoto University. The ratio of these organisms was as follows ; Staphylococcus 45.6 %, Diphtheroidbacillus 17.2 Colibacillus 12.9 %, grampositive Diplococcus 8.8 %, Streptococcus 7.2 %, Proteusbacillus 6.4 %, Micrococcus catarrhalis 1.6 %, Streptobacillus Ducrey-like-organism 0.3 %, and abacterial was 9.7 %. Mixed infection was found in 66 cases (22.9 %), 48 cases had two kinds, 17 cases had 3 kinds and one case has 4 kinds of organisms. As to 53 strains of these organisms, sensitivity to 7 antibiotics (P e , SM, CM, AM, TM, TC, EM) was measured in vitro, and it was found that many strains revealed strong resistance. Particularly, they have had a powerful resistance to the antibiotics which had been used previously. As to 2 strains of Staphylococcus albus and each one strain of Staphylococcus aureus, Streptococcus haemolyticus, Diphthero .idbacillus and Colibacillus, both development and decline of resistance to 7 antibiotics were observed in ritro. It was shown that they development the most powerful resistance to SM and their came Pe, CM, TC, AM, EM, TM in order. The organisms which h ad the strong resistance from the biginning of the culture gained less development of resistance in generally, and the decline of resistance was found in about one third of all organisms tested in this study, but the tendency of its decline was not remarkable.