小胃による代用膀胱の実験的研究 第2篇:小胃の吸収に及ぼす滲透圧及び分泌機能の影響

Abstract

As reported previously, the absorption of chlorin e by the segment of stomach is markedly less than that by the other intestinal canal. Concerning the fundamental experime n t of the substitute bladder from the segment of stomach further investigation is presented here. This paper deals with the influences of the o s m otic pessuke of injected fluid and the gas— tric secreting function upon the absorption by the segment of stomach. At first Heidenhain's pouch was made up of the segme n t of corpus ventriculi of mongrel dogs. When a certain time has passed after the injection of hypo-, iso- and hypertonic salt solutions and human urine labeled with radioative isotope C136 into the pouch respectively, the fluid volume, Cl and C136 in the fluid withdrawn from the pouch, were determined in. regard to the resting phase and the secreting phase of stomach. Obtained results were as follows 1) The pouch can be well s upplied with blood and widely mobile, if only left gastroepiploic vessels are reserved with the pouch. 2) When fluid was kept in the po u ch for a long time, it began to become gradually isotonic. Consequently the exchange of water and chlorine was recognized between the blood and the internal space of pouch through the wall of it. 3) The more hypekonic was the injected fluid, the h igher was the rate of the chlorine absotrtion, and when the fluid was reserved for a long time, pretty volume of chlorine was absorbed. 4 ) The significiant difference was not recognized between the resting and secreting phase in respect to the absorption of CI36.