人体泌尿器腫瘍の家兎眼前房内移植 第1編:予備実験

Abstract

Factors influencing heterogenous cultivation of tum o r of human G-U organs removed by surgery in the ocular anterior chamber of rabbits were discussed. The best results were obtained when a germ to be cultivated was 2 cubic millimeters in size, while its suspension and homogenate failed to be cultivated and a substance accelerating propagation of cultivated tumor did not create better results. A sterile and fresh germ should be sticked tightly to the iris and cornea at the anterior chamber angle (Angulus iridocornealis). Younger the rabbits, better will be the results. Sex of rabbit influencing to the results depends upon the nature of tumor. Propagation of cultivated tumor was markedly improved by administration of cortisone, thorium, or X-Ray radiation. Cortisone must be administered daily, while eye drop of cortisone also be effective and practical when a large series of rabbits are employed. Cultivation of successive generation in untreated grown rabbit was not successful and duplicated cultivation was barely successful.