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タイトル: | 尿路感染症に対するスペクチノマイシンの使用経験 |
その他のタイトル: | Use of Spectinomycin for urinary tract infections |
著者: | 重松, 俊 江藤, 耕作 高田, 千年 樋口, 正士 |
著者名の別形: | SHIGEMATSU, Shun ETO, Kosaku TAKADA, Chitose HIGUCHI, Masahito |
キーワード: | Adult Aged Anti-Bacterial Agents/therapeutic use Female Humans Male Middle Aged Urinary Tract Infections/drug therapy |
発行日: | Jun-1966 |
出版者: | 京都大学医学部泌尿器科学教室 |
誌名: | 泌尿器科紀要 |
巻: | 12 |
号: | 6 |
開始ページ: | 602 |
終了ページ: | 605 |
抄録: | A new antibiotic, Spectinomycin (SPE), was administered to patients with urinary tract infections. The results obtained are summarized as follows. 1) Blood level : Blood concetration of SPE showed th e peak level at one hour after intramuscular injection of 800 mg, which was 5.83 mcg/ml as the maximum, with a subsequent gradual decrease until at twelve hours when only trace level, 0.18 mcg/ml, was found. 2) Urinary excretion : The total amount of urinary excretion of SPE up to 12 hours after intramuscular injection of 800 mg SPE was 564.69 mg with the recovery rate being 70.5 %. 3 ) Clinical effectiveness : SPE was administered to 17 patients with various urinary infections. Excellent, good and poor results were obtained in 9, 5 and 3 cases respectively, showing effectiveness 82.3 % (14 cases). SPE was particularly beneficial in 11 cases of acute urinary infections with the effectiveness being 100 %. 4) Side effects : No. noticeable side effect was observe d in all of the cases treated. |
URI: | http://hdl.handle.net/2433/112968 |
PubMed ID: | 6006920 |
出現コレクション: | Vol.12 No.6 |
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