泌尿器科領域に於けるLysozymeの臨床的応用

Abstract

Lysozyme was administered to 74 patients seen at the department of urology of the Kyoto University Hospital and was supposed to have indication of the drug. The results are summarized as follows. 1) Fifteen patients with cystitis were treated with chemotherapy in combination with Lysozyme. Lysozyme was found to be effective in 5 cases and slight effective in 4 cases, with the effectiveness being 60.0 %. 2) Six patients with pyelon e phritis were given chemotherapy accompanied with of Lysozyme. Effective and slight effective results of Lysozyme were obtained in one case respectively. 3) Seven patients with essential renal bleeding were treated with Lysozyme. In 1 case, complete disappearance of hematuria was observed with subsequent reappearance in 2 months. In another 2 cases, the grade of hematuria was slightly improved. 4) Four patients with hemospermia were put on Lysozyme. One patient with an episode of hemospermia showed complete cure following the administration. 5) Eighteen cases in whom intratracheal anesthesia wa s performed were given Lysozyme to observe releasing effect of the drug on laryngeal irritation. The drug was effective or slightly in 8 and 7 cases respectively, with the effectiveness being 83.5 %. 6) Eleven operated cases in whom the urinary tract was aggressed were given Lysozyme to observe bacteriocidal, antibiotics intensified, anti-inflammatory and antiedematous effects of the drug. Both of effective or slight effective results were 4 cases respectively with the effectiveness being 72.6 %. 7) Twenty-one cases operated on phimos i s or intrascrotal procedures were treated with Lysozyme to see anti-edemetous and anti-inflammatory effects. Effective and slight effective results were obtained in 12 and 3 cases respectively, with the effectiveness being 72.6 %. 8 ) Three cases of terminal cancer were given Lysozyme which released pain in 2 and improved general conditions in 1 case.