頻尿に対する牛車腎気丸の効果

Abstract

下部尿路症状にて内服治療を行うも頻尿症状の改善が不十分であった前立腺疾患20例に対し, 牛車腎気丸の併用し, その効果について検討した.内服薬は塩酸タムスロシン10例, ナフトピジル7例, 酢酸クロルマジノン1例, 塩酸プロピベリン6例で, 牛車腎気丸投与開始後も投与を継続した.1)有効率は昼間頻尿で45%, 夜間頻尿で65%であった.2)頻尿に対する効果は投与4週後で認められたが, 尿流量率, 残尿量の改善は投与8週後に認められた.したがって, 下部尿路症状の改善には少なくとも8週間の投与が必要であると考えられた

We investigated the efficacy of Gosyajinkigan in 20 patients with prostatic disease, in whom pollakisuria was not improved by treatment with drugs for lower urinary tract symptoms. Four and 8 weeks after treatment, the urinary frequency was significantly improved during both daytime and night. The efficacy rates for diurnal frequency and nocturia were 45% and 65%, respectively. The International Prostate Symptom Score (IPSS) was decreased 4 weeks after treatment, and the parameters of uroflowmetry, the residual urine volume and quality of life score were improved 8 weeks after therapy. It was concluded that Goshajinkigan was effective for pollakisuria with prostatic disease, and the administration of the agent for 8 weeks or longer was needed to improve lower urinary tract symptoms.