異時性に孤立性副腎転移をきたした腎細胞癌の3例

Abstract

異時性に副腎転移をきたした腎細胞癌の3例(43歳女, 53歳女, 56歳男)を経験した.1例は同側副腎転移, 2例は対側副腎転移であった. 1)腎細胞癌の術後長期間を経て副腎転移をきたす例があり, 長期にわたる定期的経過観察を行う必要がある. 2)腎細胞癌の副腎転移に対しては現状では積極的手術療法が望ましい

We report 3 cases of renal cell carcinoma (RCC) with solitary asynchronous adrenal metastasis. Case 1; A 43-year-old female was diagnosed with ipsilateral adrenal metastasis 10 years after nephrectomy of RCC (T2, N0, M0). She is alive with no evidence of disease five years after adrenalectomy. Case 2; A 53-year-old female had contralateral adrenal metastasis 10 years after nephrectomy (T3, N0, M0). She died with distant metastasis fourteen months post-operatively. Case 3; A 56-year-old man was diagnosed with contralateral adrenal metastasis 3 years after nephrectomy (T3, N0, M0). He is alive with no evidence of disease twenty months postoperatively. Two of our three cases are alive and tumor-free. However, adrenal metastasis was found in case 1 and case 2, even though more than ten years had passed after nephrectomy. Therefore we should observe the patients periodically after radical nephrectomy for a long time.