慢性非細菌性前立腺炎及び前立腺痛における血清抗Chlamydia trachomatis抗体検査と臨床的検討

Abstract

慢性非細菌性前立腺炎症例41例及び前立腺痛症例47例を対象として, 血清抗C.trachomatis抗体検査を行い, EPS/VB3中の白血球数を指標とした炎症所見及び症状との関連を検討した. 1)IgG抗体陽性率は前立腺痛症例で28%, 慢性非細菌性前立腺炎症例で29%であり, 炎症所見との関連は認められなかった.IgA抗体陽性率は前立腺痛症例で9%, 慢性非細菌性前立腺炎症例で5%であった. 2)排尿に関する症状と関連痛に関する症状の間でC.trachomatis抗体陽性率に差は認めなかったが, 血精液症では, IgG抗体陽性者が5名中4名と高率に認められ, 血精液症とC.trachomatisとの関連が示唆された

The etiological role of Chlamydia trachomatis in chronic nonbacterial prostatitis is controversial. To assess whether C. trachomatis relates to chronic nonbacterial prostatitis, we investigated the serum levels of immunoglobulin G (IgG) and IgA antibodies specific for C. trachomatis in 41 patients with chronic nonbacterial prostatitis and 47 patients with prostatodynia. The positive rates of the IgG antibody were 29% and 28% in patients with chronic nonbacterial prostatitis and prostatodynia, respectively. There was little difference in the positive rates of the IgG and IgA antibodies for C. trachomatis, between patients with chronic nonbacterial prostatitis and prostatodynia. Also, there was no significant difference in the positive rate of the IgG antibody between 51 patients complaining of urinary symptoms and 25 complaining of referred pain. However, a high positive rate of the IgG antibody (80%) was observed in patients with hematospermia. Our findings suggest that C. trachomatis could not be etiologically responsible for chronic nonbacterial prostatitis, but that it may be related to hematospermia.