腹圧性尿失禁に対する経尿道的コラーゲン注入療法 特に自覚症状での検討

Abstract

女性25例に計31回施行した. 1)術後1ヵ月で予後効果判定が可能と考えられた. 2)尿失禁完全消失・改善症例と不変症例の間で, 年齢・type別・pad test・注入量において有意差は認めなかった. 3)2回以上注入した症例のうち腹圧性尿失禁type IIIでは効果が認められた. 4)術後3ヵ月時点で効果のあった症例では, 全例悪化した場合再注入の希望があった. 5)本療法は, 低侵襲的で第一選択となりうる

We evaluated the results of transurethral collagen injections for urinary stress incontinence. Twenty five women (mean age was 61.3 years) with urinary incontinence were treated with transurethral collagen injections using local or spinal anesthesia. The mean follow-up was 11.7 months (range 2 to 30). We examined the results based on subjective symptoms for incontinence. We could judge convalescence efficacy to some degree 1 month after operation, but patient age, type of stress incontinence, pad test and volume of collagen were not significantly different between patients who were cured and those not cured. Of the patients who needed injections more then 2 times, treatment was effective in type III patients. The patients whose symptoms were improved 3 months after operation wanted a re-operation when their incontinence recurred. Injection of transurethral collagen appears to be a safe and effective method for treating urinary incontinence. This procedure is a first choice for urinary incontinence.