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dc.contributor.author | 内藤, 誠二 | ja |
dc.contributor.author | 熊澤, 浄一 | ja |
dc.contributor.alternative | NAITO, Seiji | en |
dc.contributor.alternative | KUMAZAWA, Joichi | en |
dc.date.accessioned | 2010-06-01T02:07:55Z | - |
dc.date.available | 2010-06-01T02:07:55Z | - |
dc.date.issued | 1989-12 | - |
dc.identifier.issn | 0018-1994 | - |
dc.identifier.uri | http://hdl.handle.net/2433/116788 | - |
dc.description.abstract | Clinical and statistical observations were made on a group of 438 persons who had worked with aromatic amines (benzidine, 2-naphthylamine, 1-naphthylamine and dianisidine) with reference to their carcinogenic properties in the urinary tract. Urinary tract tumors developed in 68 (15.5%), with an average latent period of 22 years and 11 months. In these 68 cases, upper urinary tract tumors were found in 16 cases, 8 of which had bilateral lesions. The average age of onset was 48.1 ranging from 24 to 79. The incidence of tumors increased with the length of exposure to the amines. There was no finding that smoking habit increased the incidence of tumors in this group. Of the 49 new patients with bladder tumor, urine cytology was positive in 24 (49.0%) and suspicious of malignancy in 10 (20.4%), respectively. This indicated that it could be a useful screening test. Transurethral surgery was most frequently performed as an initial treatment. Recurrence occurred in 50 cases (73.5%), but 5-, 10- and 20-year-survival rates were 89.0 79.3 and 64.7%, respectively, showing a good prognosis. Malignant tumors in other organs developed in 18 (4.1%) of the 438 workers. The incidence of such malignant tumors was significantly higher in the workers who had been exposed to 2-naphthylamine than in others. Our data indicate that close observation is still necessary for early detection of patient with new or recurrent urothelial carcinoma in this group. | en |
dc.format.mimetype | application/pdf | - |
dc.language.iso | jpn | - |
dc.publisher | 泌尿器科紀要刊行会 | ja |
dc.subject | Occupational urothelial cancer | en |
dc.subject | Benzidine | en |
dc.subject | 2-Naphthylamine | en |
dc.subject | 1-Naphthylamine | en |
dc.subject | Dian- isidine | en |
dc.subject.ndc | 494.9 | - |
dc.title | 芳香族アミン化合物による尿路腫瘍 | ja |
dc.title.alternative | Urothelial carcinoma related to exposure to aromatic amines | en |
dc.type | departmental bulletin paper | - |
dc.type.niitype | Departmental Bulletin Paper | - |
dc.identifier.ncid | AN00208315 | - |
dc.identifier.jtitle | 泌尿器科紀要 | ja |
dc.identifier.volume | 35 | - |
dc.identifier.issue | 12 | - |
dc.identifier.spage | 2023 | - |
dc.identifier.epage | 2031 | - |
dc.textversion | publisher | - |
dc.sortkey | 06 | - |
dc.address | 九州大学医学部泌尿器科学教室 | ja |
dc.address | 九州大学医学部泌尿器科学教室 | ja |
dc.address.alternative | Department of Urology, Faculty of Medicine, Kyushu University | en |
dc.address.alternative | Department of Urology, Faculty of Medicine, Kyushu University | en |
dc.identifier.pmid | 2618901 | - |
dcterms.accessRights | open access | - |
dc.identifier.pissn | 0018-1994 | - |
dc.identifier.jtitle-alternative | Acta urologica Japonica | la |
dc.identifier.jtitle-alternative | Hinyokika Kiyo | en |
出現コレクション: | Vol.35 No.12 |
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