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タイトル: | Ciprofloxacin三日間連続投与後の前立腺組織内濃度について |
その他のタイトル: | Ciprofloxacin concentration in human prostatic tissue following 3 days' administration |
著者: | 森田, 昌良 中川, 晴夫 鈴木, 騏一 |
著者名の別形: | Morita, Masayoshi Nakagawa, Haruo Suzuki, Kiichi |
キーワード: | Ciprofloxacin Prostatic concentration |
発行日: | May-1991 |
出版者: | 泌尿器科紀要刊行会 |
誌名: | 泌尿器科紀要 |
巻: | 37 |
号: | 5 |
開始ページ: | 563 |
終了ページ: | 566 |
抄録: | The penetration of Ciprofloxacin (CPFX) into the prostatic tissue and the serum was examined. Forty-four patients with benign prostatic hypertrophy treated with transurethral resection of the prostate were entered in this study. CPFX was administered orally in a dose of 200 mg three times daily for three days preoperatively. The blood samples were taken simultaneously at the time of the tissue sampling. The patients were divided into groups 1 and 2. In group 1 (16 patients), the tissue sampling was done about 17 hours after the final drug administration. The mean concentration of CPFX was 0.61 +/- 0.40 microgram/g in the prostatic tissue and 0.27 +/- 0.19 micrograms/ml in the serum. In group 2 (28 patients), tissue sampling was done 5.5 hours after the final drug administration. The mean concentration of CPFX was 1.32 +/- 0.64 micrograms g in the prostatic tissue and 0.65 +/- 0.31 microgram/ml in the serum. |
URI: | http://hdl.handle.net/2433/117171 |
PubMed ID: | 1713402 |
出現コレクション: | Vol.37 No.5 |
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