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Title: 膀胱癌に対する動注化学療法後に生じた坐骨神経麻痺の2例
Other Titles: Sciatic nerve paralysis following intraarterial chemotherapy for bladder cancer: reports of two cases
Authors: 永松, 秀樹  KAKEN_name
松村, 剛  KAKEN_name
和久井, 守  KAKEN_name
Author's alias: Nagamatsu, Hideki
Matsumura, Tsuyoshi
Wakui, Mamoru
Keywords: Sciatic nerve paralysis
Intraarterial chemotherapy
Cisplatin
4'-0-tetrahydropyranyladriamycin
Bladder cancer
Issue Date: Aug-1993
Publisher: 泌尿器科紀要刊行会
Journal title: 泌尿器科紀要
Volume: 39
Issue: 8
Start page: 743
End page: 746
Abstract: Bilateral sciatic nerve paralysis developed in two patients with invasive bladder cancer following intraarterial infusion of cisplatin (CDDP) and 4'-0-tetrahydropyranyladriamycin (THP) as preoperative adjuvant chemotherapy. Balloon catheters were selectively inserted into both internal iliac arteries, and CDDP 100 mg/m2 and THP 40 mg/m2 were administered under balloon occlusion. Pain of lower extremities developed soon after infusion and was gradually followed by paralysis. One patient recovered from paralysis partially after 4 months, but the other patient didn't recover. The use of balloon catheters resulted in an excessive concentration of chemotherapeutic agents with the adverse action on the sciatic nerves.
URI: http://hdl.handle.net/2433/117904
PubMed ID: 8397481
Appears in Collections:Vol.39 No.8

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