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dc.contributor.author後藤, 修一ja
dc.contributor.author立花, 裕一ja
dc.contributor.author東, 四雄ja
dc.contributor.author福井, 厳ja
dc.contributor.author高木, 健太郎ja
dc.contributor.author竹内, 信一ja
dc.contributor.alternativeGOTOH, Shuichien
dc.contributor.alternativeTACHIBANA, Yuichien
dc.contributor.alternativeHIGASHI, Yotuoen
dc.contributor.alternativeFUKUI, Iwaoen
dc.contributor.alternativeTAKAGI, Kentaroen
dc.contributor.alternativeTAKEUCHI, Shinichien
dc.date.accessioned2010-06-02T01:40:35Z-
dc.date.available2010-06-02T01:40:35Z-
dc.date.issued1984-09-
dc.identifier.issn0018-1994-
dc.identifier.urihttp://hdl.handle.net/2433/118279-
dc.description.abstractラットではCis-diamminedichloroplatinum (DDP)投与後24日目にstage 9-10の精細管でPachytene数の減少ないし消失がみられ, この程度はdose-dependentであった.従って, DDP投与時の精上皮における障害部位は分化過程のspermatogonia A1と推測されたja
dc.description.abstractAdult male rats were injected intraperitoneally with 2 mg, 4 mg and 6 mg Cis-diamminedichloroplatinum (DDP) per kg body weight. The animals were then sacrificed on the 7th, 24th or 35th day. Two specimens of testis from each rat were stained by H.E. technique, then the Pachytene primary spermatocytes and Sertoli cells in the cross sectioned tubules at stage IV-V, IX-X and XIII-XIV were counted. Significant decrease of Pachytene/Sertoli(P/S) valueinstage IX-X tubules on the 24th day (p less than 0.01) suggests that DDP has a cytotoxic effect on early differentiated type A spermatogonia (A1).en
dc.format.mimetypeapplication/pdf-
dc.language.isojpn-
dc.publisher泌尿器科紀要刊行会ja
dc.subjectDDPen
dc.subjectSeminiferous epitheliumen
dc.subjectSpermatogoniaen
dc.subject.ndc494.9-
dc.titleDDPのラット精上皮への影響ja
dc.title.alternativeThe effects of DDP on the seminiferous epithelium of ratsen
dc.typedepartmental bulletin paper-
dc.type.niitypeDepartmental Bulletin Paper-
dc.identifier.ncidAN00208315-
dc.identifier.jtitle泌尿器科紀要ja
dc.identifier.volume30-
dc.identifier.issue9-
dc.identifier.spage1195-
dc.identifier.epage1199-
dc.textversionpublisher-
dc.sortkey08-
dc.addressあそか病院泌尿器科ja
dc.address東京医科歯科大学医学部泌尿器科学教室ja
dc.address東京医科歯科大学医学部泌尿器科学教室ja
dc.address東京医科歯科大学医学部泌尿器科学教室ja
dc.address東京医科歯科大学医学部泌尿器科学教室ja
dc.address埼玉医科大学泌尿器科学教室ja
dc.address.alternativethe Department of Urology, Asoka Hospitalen
dc.address.alternativethe Department of Urology, Tokyo Medicaland Dental University School of Medicineen
dc.address.alternativethe Department of Urology, Tokyo Medicaland Dental University School of Medicineen
dc.address.alternativethe Department of Urology, Tokyo Medicaland Dental University School of Medicineen
dc.address.alternativethe Department of Urology, Tokyo Medicaland Dental University School of Medicineen
dc.address.alternativethe Department of Urology, Saitama College of Medicineen
dc.identifier.pmid6543096-
dcterms.accessRightsopen access-
dc.identifier.pissn0018-1994-
dc.identifier.jtitle-alternativeActa urologica Japonicala
dc.identifier.jtitle-alternativeHinyokika Kiyoen
出現コレクション:Vol.30 No.9

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