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タイトル: | 膀胱癌, 腎細胞癌に対するUFTの使用経験 |
その他のタイトル: | Clinical experience of tegafur-uracil (UFT) against bladder cancer and renal cell carcinoma |
著者: | 中神, 義三 林, 昭棟 伊藤, 博 平沢, 精一 淡輪, 邦男 藤岡, 良彰 小川, 秀弥 田中, 求平 山田, 記道 石井, 洋二 引間, 規夫 |
著者名の別形: | Nakagami, Yoshizo Lin, Tsaw Tung Ito, Hiroshi Hirasawa, Seiichi Tannawa, Kunio Fujioka, Yoshiaki Ogawa, Hideya Tanaka, Kyuhei Yamada, Norimichi Ishii, Yoji Hikima, Norio |
キーワード: | Adult Aged Antineoplastic Combined Chemotherapy Protocols/therapeutic use Carcinoma, Renal Cell/drug therapy Carcinoma, Transitional Cell/drug therapy Female Humans Kidney Neoplasms/drug therapy Male Middle Aged Tegafur/administration & dosage Uracil/administration & dosage Urinary Bladder Neoplasms/drug therapy |
発行日: | Oct-1987 |
出版者: | 泌尿器科紀要刊行会 |
誌名: | 泌尿器科紀要 |
巻: | 33 |
号: | 10 |
開始ページ: | 1728 |
終了ページ: | 1732 |
抄録: | The safety of prolonged administration of UFT in which tegafur and uracil were mixed in a ratio of 1:4 in molar fraction was studied in 44 cases of bladder cancer and 10 cases of renal cell carcinoma. Daily doses of UFT were 300-600 mg, and average total doses administered were 102.0 g for bladder cancer and 116.6 g for renal cell carcinoma cases. Incidence of adverse effects were 25.0% in bladder cancer and 18.5% in renal cell carcinoma cases. Anorexia, nausea, vomiting and decrease in WBC were observed, but rates of having discontinued the administration of UFT were very low, being 9.1% in bladder cancer and 10.0% in renal cell carcinoma. Thus, UFT was considered to be tolerable during prolonged use in bladder cancer and renal cell carcinoma and also a drug in which more usefulness is expected in multidisciplinary treatments in future. |
URI: | http://hdl.handle.net/2433/119290 |
PubMed ID: | 3128071 |
出現コレクション: | Vol.33 No.10 |
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