ダウンロード数: 592
タイトル: | コロニー形成試験および〔3H〕サイミジン取り込み試験を用いた膀胱癌細胞株の放射線感受性に関する検討 |
その他のタイトル: | Assessment of the response of human bladder cancer cell lines to radiation using colony formation assay and [3H] thymidine incorporation assay |
著者: | 李, 南奎 金丸, 洋史 吉田, 修 |
著者名の別形: | Lee, Nam Kyu KANAMARU, Hiroshi YOSHIDA, Osamu |
キーワード: | Bladder cancer Radiosensitivity Colony formation assay [3H] thymidine incorporation assay |
発行日: | Jan-1988 |
出版者: | 泌尿器科紀要刊行会 |
誌名: | 泌尿器科紀要 |
巻: | 34 |
号: | 1 |
開始ページ: | 32 |
終了ページ: | 36 |
抄録: | The effect of radiation on the human bladder cancer cell lines, KK47 and J82, was studied using colony formation assay and [3H] thymidine incorporation assay. The response to radiation was dose-related for both assays, but the curve for the colony formation assay was steeper than that for [3H] thymidine incorporation assay. However, the steepness of the curve for [3H] thymidine incorporation assay increased to be approximately the same as that for the colony formation assay as the incubation period increased. [3H] Thymidine incorporation assay can provide a rapid assessment of radiation sensitivity comparable to that obtained by the colony formation assay to select a radiosensitive bladder cancer patient for definitive or adjunctive radiotherapy. |
URI: | http://hdl.handle.net/2433/119438 |
PubMed ID: | 3376803 |
出現コレクション: | Vol.34 No.1 |
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