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34_714.pdf | 5.02 MB | Adobe PDF | 見る/開く |
タイトル: | 全身転移を来した外陰部Paget 病の1例 |
その他のタイトル: | Genital Paget's disease with general metastasis: a case report |
著者: | 奥野, 博 西尾, 恭規 竹内, 秀雄 岡田, 謙一郎 吉田, 修 |
著者名の別形: | OKUNO, Hiroshi NISHIO, Yasunori TAKEUCHI, Hideo OKADA, Kenichiro YOSHIDA, Osamu |
キーワード: | Genital Paget's disease General metastasis |
発行日: | Apr-1988 |
出版者: | 泌尿器科紀要刊行会 |
誌名: | 泌尿器科紀要 |
巻: | 34 |
号: | 4 |
開始ページ: | 714 |
終了ページ: | 717 |
抄録: | A 74-year-old man with the chief complaint of ulceration of penile shaft and scrotal swelling was referred to our hospital on November 7, 1985. Biopsy specimen of the local lesion histologically revealed invasive adenocarcinoma with Paget's cell. Clinical studies revealed a high serum carcinoembryonic antigen (CEA) level and regional lymph node metastasis was highly suspected. We concluded that the patient was suffering from Stage II genital Paget's disease. Emasculation, bil-inguinal and pelvic lymph node dissection, and free skin mesh grafting were performed on December 24, 1985. Histological findings of the tumor confirmed Paget's disease and bil-inguinal and pelvic lymph node metastases. CEA staining showed CEA positive malignant cells in both the primary lesion and metastatic lymph nodes. After operation, the rapid deterioration of the patient's condition was accompanied by extremely high serum CEA levels, obstructive jaundice, and evidence of metastasis to the liver. He died 24 days after operation and autopsy could not be performed. We recommend aggressive treatment when clinical studies reveal invasion to the epidermis, high serum CEA levels and lymph node metastasis. |
URI: | http://hdl.handle.net/2433/119524 |
PubMed ID: | 2840812 |
出現コレクション: | Vol.34 No.4 |
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