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DCフィールド | 値 | 言語 |
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dc.contributor.author | 金丸, 洋史 | ja |
dc.contributor.author | 橋村, 孝幸 | ja |
dc.contributor.author | 筧, 善行 | ja |
dc.contributor.author | 李, 南杢 | ja |
dc.contributor.author | 吉田, 修 | ja |
dc.contributor.alternative | KANAMARU, Hiroshi | en |
dc.contributor.alternative | HASHIMURA, Takayuki | en |
dc.contributor.alternative | KAKEHI, Yoshiyuki | en |
dc.contributor.alternative | LEE, Nam Kyu | en |
dc.contributor.alternative | YOSHIDA, Osamu | en |
dc.date.accessioned | 2010-06-02T02:58:32Z | - |
dc.date.available | 2010-06-02T02:58:32Z | - |
dc.date.issued | 1988-11 | - |
dc.identifier.issn | 0018-1994 | - |
dc.identifier.uri | http://hdl.handle.net/2433/119779 | - |
dc.description.abstract | In vitro chemosensitivity of urological cancers was assessed by a human tumor colony forming assay (HTCA) and a 3H-thymidine incorporation assay. Primary tumor cells from 160 of 253 (63%) urological cancers showed adequate colony growth (greater than 30 colonies per well), and there was a 57% true positive and 100% true negative rate for predicting clinical response of anticancer agents. On the other hand, cells from 37 of 45 (82%) urologic cancers incorporated a sufficient amount of 3H-thymidine (greater than 300 cpm). However, when the positive control drug (chromomycin A3 100 micrograms/ml) was used for the assay quality control, the successful assay rate of the HTCA (38%) was lower than that of the 3H-thymidine incorporation assay (75%), while there was a significant correlation in drug sensitivities between the two assays. Thus, the 3H-thymidine incorporation assay seemed to be more useful than the HTCA for evaluating the chemosensitivity of urologic cancers. | en |
dc.format.mimetype | application/pdf | - |
dc.language.iso | jpn | - |
dc.publisher | 泌尿器科紀要刊行会 | ja |
dc.subject | Urological cancer | en |
dc.subject | Chemosensitivity test | en |
dc.subject | Human tumor colony forming assay | en |
dc.subject | 'H-thymidine incorporation assay | en |
dc.subject.ndc | 494.9 | - |
dc.title | Human tumor colony forming assayによる抗癌剤感受性試験について | ja |
dc.title.alternative | In vitro chemosensitivity test by human tumor colony forming assay | en |
dc.type | departmental bulletin paper | - |
dc.type.niitype | Departmental Bulletin Paper | - |
dc.identifier.ncid | AN00208315 | - |
dc.identifier.jtitle | 泌尿器科紀要 | ja |
dc.identifier.volume | 34 | - |
dc.identifier.issue | 11 | - |
dc.identifier.spage | 1917 | - |
dc.identifier.epage | 1921 | - |
dc.textversion | publisher | - |
dc.sortkey | 08 | - |
dc.address | 京都大学医学部泌尿器科学教室 | ja |
dc.address | 京都大学医学部泌尿器科学教室 | ja |
dc.address | 京都大学医学部泌尿器科学教室 | ja |
dc.address | 京都大学医学部泌尿器科学教室 | ja |
dc.address | 京都大学医学部泌尿器科学教室 | ja |
dc.address.alternative | the Department of Urology, Faculty of Medicine, Kyoto University | en |
dc.address.alternative | the Department of Urology, Faculty of Medicine, Kyoto University | en |
dc.address.alternative | the Department of Urology, Faculty of Medicine, Kyoto University | en |
dc.address.alternative | the Department of Urology, Faculty of Medicine, Kyoto University | en |
dc.address.alternative | the Department of Urology, Faculty of Medicine, Kyoto University | en |
dc.identifier.pmid | 3242365 | - |
dcterms.accessRights | open access | - |
dc.identifier.pissn | 0018-1994 | - |
dc.identifier.jtitle-alternative | Acta urologica Japonica | la |
dc.identifier.jtitle-alternative | Hinyokika Kiyo | en |
出現コレクション: | Vol.34 No.11 |
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