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タイトル: 泌尿器科領域におけるAC-PCの応用
その他のタイトル: Application of AC-PC in the field of urology
著者: 石神, 襄次  KAKEN_name
原, 信二  KAKEN_name
三田, 俊彦  KAKEN_name
著者名の別形: Ishigami, Joji
Hara, Shinji
Mita, Toshihiko
キーワード: Adolescent
Adult
Aged
Ampicillin
Child
Female
Humans
Male
Microbial Sensitivity Tests
Middle Aged
Penicillins/blood/therapeutic use/urine
Urinary Tract Infections/drug therapy
発行日: Oct-1969
出版者: 泌尿器科紀要刊行会
誌名: 泌尿器科紀要
巻: 15
号: 10
開始ページ: 735
終了ページ: 743
抄録: Basic and clinical studies with AC-PC gave the following results: 1. Antibacterial effects The sensitivity of Staphylococcus to AC-PC was well comparable to ARPC, while against E. coli the antibacterial activity was inferior to that of AB-PC. 2. Blood concentration and urinary excretion rate With 500 or 1,000 mg of oral administration, the blood concentration reached a peak, being 20.9 γ/ml and 30.7γ/ml, respectively, an hour after the intake, and henceforth the level fell rapidly, though it was measurable at 4 hours. The urinary excretion rate after oral administration was quite high, being 54.4 % of 500 mg in 6 hours. 3. Clinical effects Fifty-three cases of various urinary infection were treated with AC-PC. Twenty-three cases showed remarkable improvement, 21 good and 9 no improvement, giving 83.0 % of curative rate. 4. Side effects Five cases out of 53 complained of gastrointestinal disorder, though it was not so serious to withdraw the medication.
URI: http://hdl.handle.net/2433/120054
PubMed ID: 5390815
出現コレクション:Vol.15 No.10

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