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タイトル: | 泌尿器科領域におけるAC-PCの応用 |
その他のタイトル: | Application of AC-PC in the field of urology |
著者: | 石神, 襄次 原, 信二 三田, 俊彦 |
著者名の別形: | Ishigami, Joji Hara, Shinji Mita, Toshihiko |
キーワード: | Adolescent Adult Aged Ampicillin Child Female Humans Male Microbial Sensitivity Tests Middle Aged Penicillins/blood/therapeutic use/urine Urinary Tract Infections/drug therapy |
発行日: | Oct-1969 |
出版者: | 京都大学医学部泌尿器科学教室 |
誌名: | 泌尿器科紀要 |
巻: | 15 |
号: | 10 |
開始ページ: | 735 |
終了ページ: | 743 |
抄録: | Basic and clinical studies with AC-PC gave the following results: 1. Antibacterial effects The sensitivity of Staphylococcus to AC-PC was well comparable to ARPC, while against E. coli the antibacterial activity was inferior to that of AB-PC. 2. Blood concentration and urinary excretion rate With 500 or 1, 000 mg of oral administration, the blood concentration reached a peak, being 20.9 γ/ml and 30.7γ/ml, respectively, an hour after the intake, and henceforth the level fell rapidly, though it was measurable at 4 hours. The urinary excretion rate after oral administration was quite high, being 54.4 % of 500 mg in 6 hours. 3. Clinical effects Fifty-three cases of various urinary infection were treated with AC-PC. Twenty-three cases showed remarkable improvement, 21 good and 9 no improvement, giving 83.0 % of curative rate. 4. Side effects Five cases out of 53 complained of gastrointestinal disorder, though it was not so serious to withdraw the medication. |
URI: | http://hdl.handle.net/2433/120054 |
PubMed ID: | 5390815 |
出現コレクション: | Vol.15 No.10 |
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