精索静脈瘤の臨床的研究 : (2) 睾丸血流量(内精動脈血流量)と内精静脈血テストステロン濃度を中心に

Abstract

精索静脈瘤患者39例を対象として, 患側内精動脈血流量, 内精静脈テストステロン値, 末梢血テストステロン値, 血中LH値および血中FSH値を測定し, 本疾患との関係を検討した.左患側の内精動脈血流量の平均9.3±7.0 ml/100 g/minで対照とした前立腺癌患者との間に有意差は見られなかった.内精動脈血流量と精巣重量との間には負の相関が見られ, 精子濃度, 患側精巣のscore countおよび内精静脈血テストステロン値の間には相関は認められなかった.血中LH値と精子濃度および患側精巣score countの間に相関はなかった.血中FSH値と精子濃度との間に相関は見られなかったが, 患側精巣score countとの間に負の相関が存在した.末梢血テストステロン値の平均6.3±2.4 ng/mlと正常範囲内にあり, 血中LH値との間に相関はなく, 内精静脈血テストステロン値は平均360±271 ng/mlで血中LH値との間に負の相関が認められた

The blood flow of the internal spermatic artery which is a main testicular blood flow, serum testosterone level of the internal spermatic vein and the peripheral vein, and serum LH and FSH levels of the peripheral vein, were measured in patients with varcocele of the left side. The blood flow of the left internal spermatic artery in patients with varicocele was 3.4~23.1 (mean value 9. 3± 7.0) ml/100g/min, which was not significantly different from that of patients with prostatic carcinoma. A negative correlation was found between the blood flow of the internal spermatic artery and the weight of the left testis. No correlation was found between the blood flow of the internal spermatic artery and sperm density, score count of the testis or the serum testosterone level of the internal spermatic vein in the left side. No correlation was found between the serum LH level and the sperm density or the score count of the left testis. There was a negative relationship between the serum FSH level and score count of the left testis, although there was no relationship between the FSH level and sperm density. Of particular note was the remarkably low score count in patient with high serum FSH levels of more than 35 mIU /ml. The serum testosterone level in the peripheral blood was within the normal range (3.0~ 12.5, mean 6. 3±24 ng/ml), and it was not related to the serum LH level. The serum testosterone level of the left internal spermatic vein was between 23.4 and 991 (mean value 460 ±271) ng/ml, and it was not significantly different from that of the control group. A negative correlation was found between the serum testosterone level of the left internal spermatic vein and the serum LH level of the peripheral blood.