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Title: 男子不妊症の臨床統計
Other Titles: Clinical study of male infertility
Authors: 中本, 貴久  KAKEN_name
長藤, 達生  KAKEN_name
瀬尾, 一史  KAKEN_name
中原, 満  KAKEN_name
久米, 隆  KAKEN_name
安川, 明廣  KAKEN_name
Author's alias: Nakamoto, Takahisa
Nagafuji, Tatsuo
Seo, Kazushi
Nakahara, Mitsuru
Kume, Takashi
Yasukawa, Akihiro
Keywords: Adult
Follicle Stimulating Hormone/blood
Humans
Infertility, Male/blood/epidemiology/physiopathology
Japan
Luteinizing Hormone/blood
Male
Sperm Count
Spermatogenesis
Testis/pathology
Testosterone/blood
Issue Date: Aug-1983
Publisher: 泌尿器科紀要刊行会
Journal title: 泌尿器科紀要
Volume: 29
Issue: 8
Start page: 885
End page: 891
Abstract: 1976~1981年までに広島大学医学部附属病院泌尿器科不妊外来を受診した794例について集計した.1)不妊外来患者は男子外来患者に対して9.9%であり,年齢分布では25~34歳が全体の76%を占めていた.不妊期間は結婚後2~5年が多く,これらで全体の約57%を占めていた.2)精液検査では無精子症が32.4%,乏精子症(50×106 /ml以下)が47.7%で,この両者が全体の約80%であった.3)睾丸生検ではhypospermatogenesisが45.4%,Sertoli cell onlyが28.8%で,この両者で全体の84.2%であった.4)睾丸容積の減少にともなって血中gonadotropin (LH, FSH)は上昇したが,testosteroneは変化なかった.睾丸容積が12 ml以下ではほとんどの症例が無精子症であり,睾丸容積の減少は高度の精細管機能障害が疑われた
A statistical analysis was performed on infertile male patients who visited our urological clinic between Jan. 1976 and Dec. 1981. The incidence of infertile male was 9.9% of the total male out-patients. Age distribution of most of the patients ranged from 25 to 34 years old. Infertile period was most commonly within 5 years after they had married. In semen analysis, the cases of azoospermia and oligozoospermia (less than 50 x 10(6)/ml) accounted for 80% of all the infertile males. Testicular histology showed hypospermatogenesis or "Sertoli cell only" in most patients (more than 84.2%) who received testicular biopsy. Decrease in testicular volume was accompanied by an increase in the serum levels of luteinizing hormone and follicle stimulating hormone, but there was no relationship between testicular volume and testosterone. Most of the patients with a testicular volume of less than 12 ml were azoospermic. This suggests that there may be a suppression of spermatogenesis in small testes.
URI: http://hdl.handle.net/2433/120227
PubMed ID: 6426271
Appears in Collections:Vol.29 No.8

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