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Title: 泌尿器科領域におけるCarbenicillinの使用経験
Other Titles: Use of carbenicillin in urological practice
Authors: 杉田, 篤生  KAKEN_name
小津, 堅輔  KAKEN_name
石崎, 允  KAKEN_name
新井, 元凱  KAKEN_name
川村, 俊三  KAKEN_name
鈴木, 騏一  KAKEN_name
Author's alias: Sugita, Atsuo
Ozu, Kensuke
Ishizaki, Mitsuru
Arai, Motoyoshi
Kawamura, Syuzo
Suzuki, Kiichi
Keywords: Acute Disease
Injections, Intramuscular
Injections, Intravenous
Microbial Sensitivity Tests
Middle Aged
Penicillins/adverse effects/pharmacology/therapeutic use
Pyelonephritis/drug therapy
Issue Date: Jun-1970
Publisher: 京都大学医学部泌尿器科学教室
Journal title: 泌尿器科紀要
Volume: 16
Issue: 6
Start page: 308
End page: 314
Abstract: Thirty-one cases of pyelonephritis were treated with carbenicillin (CB-Pc). Five were given 4 g×7 days, twenty-five given 4 g x 14 days and one 16 g×10days. Evaluation of the clinical response was made based on changes in fever, leukocytosis, pyuria and urinary bacteria. The results were as follows: excellent 11, good 10, fair 3 and non-effective 1. Six cases showed alteration of microbial flora. Thus, effective cases were counted as 21 with effectiveness rate 67.7 %. Of five cases from which urine Pseudomonas aeruginosa was isolated, one showed very good response and three good. Effectiveness rate in this group was therefore 80.0 %. No side effects were observed except for slight swelling and redness of i.m. injection site in two cases. Even in six cases with impaired renal function, further aggravation due to the drug was never noted. From the above findings, CB-Pc could be regarded as a useful antibiotic against urinary tract infection.
PubMed ID: 5465255
Appears in Collections:Vol.16 No.6

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