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| ファイル | 記述 | サイズ | フォーマット | |
|---|---|---|---|---|
| 16_0586.pdf | 505.23 kB | Adobe PDF | 見る/開く |
| タイトル: | 膀胱癌再発に対するDiacetyl-glucaro-(1→4)(6→3)-dilactone(SLA)投与の検討 |
| その他のタイトル: | Diacetyl-glucaro-(1 leads to 4) (6 leads to 3)-dilactone (SLA) for prevention of bladder tumor recurrence |
| 著者: | 白石, 恒雄  仁平, 寛巳 |
| 著者名の別形: | Shiraishi, Tsuneo Nihira, Hiromi |
| キーワード: | Acetates/therapeutic use Adipic Acids/therapeutic use Adult Aged Female Glucuronidase/antagonists & inhibitors Humans Lactones/therapeutic use Male Middle Aged Neoplasm Recurrence, Local/prevention & control Urinary Bladder Neoplasms/drug therapy/prevention & control/surgery |
| 発行日: | Oct-1970 |
| 出版者: | 京都大学医学部泌尿器科学教室 |
| 誌名: | 泌尿器科紀要 |
| 巻: | 16 |
| 号: | 10 |
| 開始ページ: | 586 |
| 終了ページ: | 592 |
| 抄録: | 1) 1.5 g/day of SLA was administered to 51 bladder tumor patients postoperatively for 3 to 46 months. Twenty-one patients were treated more than 24 months. The tumor recurrence was noted in 39.2 %, whereas it was 56.7 % in the control group. 2) Urinary J3-glucuronidase activity was inhibited by administration of SLA. In conjunction with Boyland's hypothesis on tumorigenesis of the urinary bladder, the preventive effect of SLA on tumor recurrence was conjectured. 3) Even in such a long-term administration of SLA, no side-effects were observed except for slight gastrointestinal disorder which required no discontinuation of the drug. |
| URI: | http://hdl.handle.net/2433/121179 |
| PubMed ID: | 5529995 |
| 出現コレクション: | Vol.16 No.10 |
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