女子急性膀胱炎に対するCephalexinならびにCephaloglycinのDouble-blind法による臨床効果について

Abstract

Cephalexin and cephaloglycin was evaluated by double blind method in 32 female cases of acute cystitis. The dosage for each drug was 1.0 g per day or 1.5 g per day for 5 days. No statistically significant difference of clinical response was observed among 4 dosage groups of the drugs and the results of bacteriological investigation showed that the both drugs have broad antibacterial activity and good susceptibility. Thus, cephalexin and cephaloglycin were evaluated as drug to be very effective for urinary tract infections. As far as the criteria for evaluation of clinical response is concerned, we established a criteria consisting of clinical symptoms and laboratory findings and tried to compare it with other criteria already reported. It is considered that our criteria have a rationale, and that a more rational criteria should be standardized as soon as possible.