Klinefelter症候群における睾丸間細胞の電子顕微鏡的観察

Abstract

Testicular biopsy was performed in two cases of XXY and one case of XX/XXY Klinefelter's syndrome, and electron microscopic observation was made in regard to the interstitial cells. Smooth surfaced endoplasmic reticula were abundantly seen in cytoplasm, while rough surfaced endoplasmic reticula were sparsely seen. Intensely osmiophilic lipochrome pigments were more abundantly found scattered in the cytoplasm than in that of normal interstitial cell. Fibrillar materials consisting of 3 to 8 filaments with a regular cross striation were frequently seen and a hypothesis linking these structures with the formation of the crystalloid of Reinke is discussed.