膀胱腫瘍に対するCarboquoneの膀胱内注入療法

Abstract

Carboquone(CQ) was given to 7 patients with vesical tumor by instillation into the bladder. Doses of 10 mg of CQ in 100 ml of normal saline solution were administered every other day to the total amount of 100 mg of CQ. The effect of the drug was evaluated on cystoscopic findings as well as histological findings. When the tumor disappeared, the drug was considered to be markedly effective. When the shrinkage of the tumor was more than 50% in size as compared with the initial size of the tumor, it was judged as effective. When the shrinkage was less than 50%, it was considered to be a little effective. When no shrinkage or increase in size was observed, it was regarded as non-effective. If evaluated according to above criteria, the drug was markedly effective in 2 cases, effective in 2 cases, a little effective in 1 case and non-effective in I case. There was one case that could not be judged because the patient did not vist the hospital. Two patients complained of burning on urination, and decrease of WBC count was found in 2 cases.