膀胱上皮内癌より浸潤癌に移行したと考えられる症例

Abstract

Three cases of invasive bladder cancer which seemed to have developed from so-called flat carcinoma in situ were reported. All of these were without known carcinogenic exposure or previous bladder malignancies. Usually, the diagnosis of bladder cancer relies on cystoscopy, but some cases, although rare, cannot be diagnosed by cystoscopy. Review of literature shows that carcinoma in situ simulates chronic cystitis not only in symptoms but also in cystoscopic findings. The important examinations to make the correct diagnosis of the urothelial changes are urine cytology, detailed cystoscopic evaluation and multiple biopsies. We think that early total cystectomy is the only complete curable treatment for these cancers.