小児急性リンパ性白血病の寛解期における睾丸浸潤の1例

Abstract

A case was reported of a testicular infiltration in childhood lymphocytic leukemia during bone marrow remission. A 2-year-old boy was admitted with 7 weeks history of general fatigue, paleness and subfever in February 1974, and was diagnosed as acute lymphocytic leukemia. Initially treated with glucocorticoid and vincristine, and subsequently maintained on the prophylactic therapy with central nervous system irradiation and intrathecal methotrxate, he kept a complete remission state for two years. On the second admission, in March 1976, he developed a painless swelling of the right testis which subsided following local irradiation. On the third admission in November 1976, a hematological relapse made him on chemotherapy with a result of a normal myelogram. He was admitted for the fourth time due to reswelling of the right testis in January 1977 while bone marrow remission. Histologic finding of the removed testis and epididymis revealed a leukemic infiltration. Two months later he developed another mass on the opposite side of the scrotum. Literature was reviewed briefly on the clinical cases with testicular swelling during the course of leukemia.