慢性膀胱炎との鑑別が困難であった膀胱上皮内癌の3例

Abstract

Three cases of the urinary bladder carcinomas in situ and the invasive carcinomas developed from carcinoma in situ of the bladder simulating chronic cystitis cystoscopically, were reported. The chief complaints of these three patients were persistent frequent urination and burning on urination, but there were no obstructive lesion of the lower urinary tract and no episode of gross hematuria. They were all male ranging 53 to 71 years old and had been smoking cigarettes since their youth. In all the cases, antibiotic chemotherapy was not effective and the diagnosis of the urinary bladder carcinomas was made by repeated cytology of urine and transurethral biopsy of the bladder lesion, and pathological diagnosis was transitional cell carcinoma of advanced stage and high grade. Partial cystectomy following total cystectomy and radiation therapy was made in a case who died of disseminated cancer 16 months after total cystectomy. Other two cases were treated by total cystectomy and have been alive without recurrence or metastasis of cancer for 13 months or 15 months since the surgery respectively. Seventeen cases resembling our cases could be collected from literature.