職業性膀胱癌を第1癌とする異時性重複癌の4例

Abstract

Since 1967, ninety dyestuff workers who had been exposed to aromatic amine have been subjected to periodic urinary cytology test (Papanicolaou's). Twenty out of ninety dyestuff workers were found to have bladder tumors including a case of asynchronous bilateral ureteral tumor. In those cases, occupational double cancer was found in four cases. Four cases of occupational metachronous double cancer as follow were reported. Case 1 was a 56-year-old dyestuff worker (man) with bladder cancer (transitional cell carcinoma) and left lung cancer (adenocarcinoma). Case 2 was a 56-year-old-dyestuff worker (man) with bladder cancer (transitional cell carcinoma) and hepatoma. Case 3 was a 43-year-old dyestuff worker (man) with bladder cancer (transitional cell carcinoma) and bile duct cancer (adenocarcinoma). Case 4 was a 61-year-old dyestuff worker (man) with bladder cancer (transitional cell carcinoma) and non-hormonal adrenocortical cancer.