XYY症候群の1例

Abstract

A case of 47, XYY chromosomal complement is reported. A 31-year-old man was refered to us on August 17, 1979 for evaluation of his fertility. The father was 24 and the mother was 34 years old when he was born. The findings on physical examination were as following: His height was 176 cm and weight 58 kg. Both testes were firm and measured 3.4×1.2 cm on the right and 3.3×1.2 cm on the left. The penile growth was normal. Plasma gonadotropin and androgen levels were all within normal limits. Analysis of the semen specimen showed one million spermatozoa/ml, 10% of motility and 60% of morphorogically abnormal cells. The testicular biopsy specimen revealed hypospermatogenesis and normal appearing Sertoli and Leydig cells. Chromosomal analysis from the peripheral leucocyte showed 47, XYY Karyotype. Testicular function of 47, XYY man was briefly discussed.