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タイトル: | DRL-917キットによる前立腺酸性フォスファターゼ測定法の検討 |
その他のタイトル: | STUDIES ON RADIOIMMUNOASSAY OF PROSTATIC ACID PHOSPHATASE BY DRL-917 KIT |
著者: | 森下, 直由 小川, 繁晴 斉藤, 泰 近藤, 厚 |
著者名の別形: | Morishita, Naoyoshi Ogawa, Shigeharu Saito, Yutaka Kondo, Atsushi |
発行日: | Jul-1980 |
出版者: | 京都大学医学部泌尿器科学教室 |
誌名: | 泌尿器科紀要 |
巻: | 26 |
号: | 7 |
開始ページ: | 899 |
終了ページ: | 904 |
抄録: | Prostatic acid phosphatase (PAP) concentrations were measured by radioimmunoassay (RIA) kit (DRL-917). 1) The coefficients of variance of PAP concentrations in inter-assay and intra-assay were 9.81±4.45% and 7.89±2.45%. 2) The recovery rates in dilution test and recovery test were 98.75±7.93% and 97.05±7.43%. 3) Significant correlation (r=0.687, p<0.01) was seen between enzymatic assay (Bessey-Lowry method) and RIA (PAP concentrations> 2.0 ng/ml). 4) There was no sex difference of PAP concentrations in normal adults, such as 0.417 ±0.411 ng/ml (n=52) in normal males and 0.435±0.577 ng/ml (n=10) in normal females, and the correlation between PAP concentration and aging was not significant. 5) All of the untreated patients and 65.5% of the treated patients with prostatic cancer of stage D had higher PAP concentrations than 2.0 ng/ml in sera, and RIA of PAP seemed to be more specific to prostatic cancer than enzymatic assay in which 91.6% and 23.3% of those had increased activities. But PAP concentrations were elevated falsely in 2 out of 11 patients with benign prostatic hyperplasia. |
URI: | http://hdl.handle.net/2433/122682 |
出現コレクション: | Vol.26 No.7 |
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