前立腺肥大症患者における膀胱機能とAcetylcholinesterase活性の検討

Abstract

Acetylcholinesterase activity in the vesical wall was measured biochemically from 24 cases with benign prostatic hypertrophy and 3 cases with normal vesical function. Our biochemical method is based on Goto's method. Acetylcholinesterase activity of the benign prostatic hypertrophy group was significantly high than the control (p<0.025). The ratio of acetylcholinesterase to total cholinesterase was elevated significantly (p<0.05). The relation between vesical functions and acetylcholinesterase activity of the vesical wall was examined. In the cases having prostatic weight over 30 grams, high acetylcholinesterase activity was found. Vesical capacity, residual urine and maximum voiding pressure showed no significant relation with this enzyme activity.