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タイトル: | Prostaglandin F2α誘導体(ONO-995・CD)の神経因性膀胱に対する作用に関する実験的研究 |
その他のタイトル: | AN EXPERIMENTAL STUDY OF THE DERIVATIVE (ONO-995・CD)OF PROSTAGLANDIN F2α ON THE EFFECT ON NEUROGENIC BLADDER |
著者: | 中新井, 邦夫 山田, 薫 大園, 誠一郎 愛下, 秀毅 柴田, 邦治 森村, 武士 |
著者名の別形: | Nakaarai, Kunio Yamada, Kaoru Ozono, Seiichiro Aishita, Hideki Shibata, Kuniharu Morimura, Takeshi |
発行日: | Jun-1981 |
出版者: | 京都大学医学部泌尿器科学教室 |
誌名: | 泌尿器科紀要 |
巻: | 27 |
号: | 6 |
開始ページ: | 669 |
終了ページ: | 676 |
抄録: | The effect of ONO-995. CD that was a derivative of prostaglandin F2a, on the neurogenic bladder was experimentally studied on rabbits with spinal cord injuries. Cystometrogram, EMG of the trigonal muscle of the urinary bladder, EMG of the bulbocavernosus muscle and electrical activity of the fourth sacral nerve or pelvic nerve were studied. The most predominant effects were obtained on the group of lower motor neuron lesion. Increased rhythmical contraction as well as contraction pressure and increased frequency as well as amplitude of EMG of the trigonal muscle were most predominant changes produced by ONO-995. CD. These results show that ONO-995. CD has a productive effect on voiding efficiency in neurogenic bladder. This effect was equally produced by oral use as well as intravenous use. |
URI: | http://hdl.handle.net/2433/122907 |
出現コレクション: | Vol.27 No.6 |
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