NCS膀胱内注入療法

Abstract

Topical bladder instillation therapy with 10, 000 units of NCS was performed on 22 patients with bladder tumors. One course of the therapy consisted of the instillation for 20 times. The following results were obtained: 1) NCS was not detected in the serum before and after the instillation in the selected 3 patients. In the tumors NCS level was slightly higher than that in the serum. 2) In 4 (18%) of the 22 patients the tumors disappeared completely. One patient (5%) showed partial disappearance and remaining 17 patients (77%) no response. Therefore, the total response rate was 23 per cent. 3) From our studies, this therapy was thought to be effective in low stage, low grade, papillary and single tumors of small size. 4) The local side effects were observed in 10 patients (45%), while no general untoward effect was observed.