前立腺肉腫の1剖検例

Abstract

A 24-year old man with the chief complaint of total urinary retention was referred to our hospital in April, 1980. Physical examination revealed a tumor in the left lobe of the prostate. Prostatic needle biopsy showed spindle cell sarcoma. One course of cyvadic-therapy was given preoperatively and the tumor was moderately reduced in size. Total cystoprostatectomy with pelvic lymph adenectomy was performed on June 4th, 1980. Histological findings of the tumor revealed malignant mesenchyoma and no lymph nodes metastases were found. After the operation, 1 course of cyvadic regimen was given but, 9 months after the operation, lower abdominal tumor was palpable and a cytology of the tumor showed local recurrence of the disease. The patient underwent operation (removal of tumor and rectosigmoid colon, colostomy). Then the pelvic mass was irradiated (a total of 4130 rads). Third course of cyvadic regimen was given, but the lower abdominal mass continued to enlarge. The patient died in July, 1981, a year and 3 months after the appearance of the first symptom and I year and I month after cystoprostatectomy. At autopsy, a local recurrent tumor of 11×7 ×7cm was found in the pelvic cavity. Multiple small (1cm) metastases were found in the lung but no lymph nodes metastasis was identified. Thirty-two Japanese cases of prostatic sarcoma during the last 8 years are reviewed.