Cushing症候群を呈した副腎皮質癌の1例

Abstract

We report a case of adrenal cortical carcinoma presenting signs of Cushing's syndrome. The patient was a 56-year-old housewife. She was hospitalized on November 14, 1979, with the chief complaints of headache, obesity, and hypertension. She had had these chief complaints for two years, but had not received any treatment. No evident findings of distant metastasis were obtained by the preoperative examination. The patient received left adrenalectomy on December 10, 1979. Histologically, the case was carcinoma of the adrenal cortex composed of clear cells and compact cells, and had advanced to stage 3. Six months later, o, p' -DDD was administered to treat the recurrence and metastasis of the cancer. Therapy was ineffective, and the patient died on February 2, 1981. At present, o, p'-DDD is used only in inoperable cases. It seemg necessary, however, to investigate its value as a rneans of preventing recurrence.