遠隔転移を有する腎細胞癌の4治療例

Abstract

Of 14 patients with renal cell carcinoma seen at our department from January 1971 through December 1980, 3 patients with distant metastases seen at diagnosis and an interesting case of distant metastasis following nephrectomy were studied clinically. Nephrectomy was performed on 2 of the 3 patients who had distant metastases at diagnosis. Both of them died within 6 months after nephrectomy and their prognosis was very poor, but the severe flank pain disappeared postoperatively in 1 patient, and the subjective and objective symptoms improved for a while in the patient who had multiple lung metastases by treatment with N/-(2'-tetrahydrofuryl)-5-fluorouracil as postoperative adjuvant therapy. The other patient who had multiple brain metastasis received only conservative therapy, and died 5.5 months after visiting our clinic. The metastasis lesion of solitary lung metastasis developing after nephrectomy in another patient completely disappeared after irradiation. The benefits of nephrectomy br renal cell carcinoma with distant metastases seen at diagnosis, 2 adjuvant therapy and the relation between metastases and prognosis were briefly discussed.